Image 1 of 1
Image 1 of 1
Image 1 of 1
Image 1 of 1
PEG-MGF Pegylated Mechano Growth Factor
PEG-MGF is a pegylated form of Mechano Growth Factor (MGF), a splice variant of Insulin-like Growth Factor-1 (IGF-1). The addition of polyethylene glycol (PEG) significantly extends its half-life and improves stability compared to standard MGF.
Key Characteristics:
Structure: Mechano Growth Factor (IGF-1Eb) with PEGylation at the N-terminus
Half-life: Dramatically prolonged (hours vs. minutes for non-pegylated MGF)
Mechanism: Activated in response to mechanical stress or muscle damage; promotes satellite cell activation, proliferation, and differentiation
Selectivity: Primarily acts locally in muscle tissue with enhanced bioavailability due to PEGylation
Research Applications:
Muscle hypertrophy and hyperplasia studies
Muscle injury recovery and repair research
Satellite cell activation and myoblast proliferation
Post-exercise muscle regeneration models
Age-related muscle loss (sarcopenia) investigations
Tissue engineering and localized anabolic signaling studies
PEG-MGF is widely used in laboratory research for its ability to stimulate localized muscle growth and repair more effectively than standard IGF-1 or MGF. The pegylation allows for better systemic stability while maintaining its potent myogenic effects.
For laboratory research use only. Not intended for human or veterinary use.
PEG-MGF Pegylated Mechano Growth Factor
PEG-MGF is a pegylated form of Mechano Growth Factor (MGF), a splice variant of Insulin-like Growth Factor-1 (IGF-1). The addition of polyethylene glycol (PEG) significantly extends its half-life and improves stability compared to standard MGF.
Key Characteristics:
Structure: Mechano Growth Factor (IGF-1Eb) with PEGylation at the N-terminus
Half-life: Dramatically prolonged (hours vs. minutes for non-pegylated MGF)
Mechanism: Activated in response to mechanical stress or muscle damage; promotes satellite cell activation, proliferation, and differentiation
Selectivity: Primarily acts locally in muscle tissue with enhanced bioavailability due to PEGylation
Research Applications:
Muscle hypertrophy and hyperplasia studies
Muscle injury recovery and repair research
Satellite cell activation and myoblast proliferation
Post-exercise muscle regeneration models
Age-related muscle loss (sarcopenia) investigations
Tissue engineering and localized anabolic signaling studies
PEG-MGF is widely used in laboratory research for its ability to stimulate localized muscle growth and repair more effectively than standard IGF-1 or MGF. The pegylation allows for better systemic stability while maintaining its potent myogenic effects.
For laboratory research use only. Not intended for human or veterinary use.
